Menopause is a significant life event for women and is accompanied by physical and psychological changes. The aim is to study the effect of yoga therapy on stress management of menopausal women. In methodology, the study was conducted through the Department of Yoga therapy, Kasturba Hospital, Delhi in the year 2022–2023. 216 menopausal symptomatic women between the ages of 40 and 60 were tested yoga treatment (n=111) and the control group (n=105) for three months. Anthropometric measures, hormonal markers, and perimenopause symptom profile were assessed in both groups after the intervention. Results stated that 37.5% women complained of vasomotor symptoms, 42.6% women psychological symptoms, 0.6% women physical symptoms, 27.9% women sexual symptoms and 42.2% women reported the other three symptoms. Three months of yoga intervention dramatically reduced all sixteen symptoms, demonstrating its high effectiveness in treating menopausal symptoms. Pains in the back of the neck or head, low back, muscles and joints were greatly decreased. In conclusion, studies suggests that yoga could serve as a main intervention for at-risk menopausal women by promoting psychological well-being and prevention of chronic diseases.